NovoBody™ Binders: Next Generation Antibodies
Antibodies have been the cornerstone of assay development for decades.
Our NovoBody™ technology leverages state-of-the-art protein design to amplify the strengths of antibodies while addressing their limitations.
NovoBody™ binders meet the evolving demands of research and diagnostics, offering the power to develop assays with unmatched speed, performance, and the flexibility to take your products to the next level.
Key Features of NovoBodies
Computationally Designed
Small (~27 kDa), highly stable, single chain. Free from disulfides, cysteines, post translational modifications, and Fcs
Accelerated Development
Go from concept to validated binders in under two weeks
Customizable
Full control of isoelectric point (pI), stability, on/off rates, custom tags, and placement of lysine and cysteine residues
NovoBody™ Duo
Easily engineered create bivalent, biparatopic and bispecific molecules
Superior Affinity
Rapid, high affinity binding (<nM) with minimal dissociation to proteins, peptides, small molecules, and post-translational modifications (PTM)
Simple Manufacturing
Unaffected by freeze thaw. Consistent high yields in E. coli and mammalian systems for easy, scalable manufacturing
Use Case: Anti-His NovoBodies Superior to Anti-His Antibodies
The His Tag NovoBody™ specifically binds 6x, 5x, or 4x His tags at the N-terminal, C-terminal, or internal regions of fusion proteins. Engineered for exceptional performance, it delivers picomolar affinity with fast on rates and ultra-slow off rates, enabling highly sensitive detection. Widely used across affinity purification, protein capture, Bio-Layer Interferometry (BLI), ELISA, and flow cytometry, the His Tag NovoBody™ sets the standard for His-tagged protein detection.
Superior Affinity to Commercial mAbs
Superior Stability to Commercial mAbs
Anti-His NovoBody™ Binder
Catalog Number
Product Name
Tag
Conjugation
Applications
Amount
Price
Product Name
Size
His Tag NovoBody™ Binder
Twin-Strep-tag
None
Kit Features
ELISA, BLI, Capture
100 μg
$350
Product Name
Size
MB-7973Bio
His Tag NovoBody™ Binder
Twin-Strep-tag
Biotin
Kit Features
ELISA, BLI, Capture
100 μg
$400
Product Name
Size
MB-7973FITC
His Tag NovoBody™ Binder
Twin-Strep-tag
FITC
Kit Features
ELISA, BLI, Capture
100 μg
$350
Flow Cytometry Validation of MB-7973Bio
Flow cytometry validation of MB-7973FITC
Anti-His NovoBody™ Duo Binder
Catalog Number
Product Name
Tag
Conjugation
Applications
Amount
Price
Product Name
Size
His Tag NovoBody™ Duo Binder
Twin-Strep-Tag
None
Kit Features
ELISA, Flow Cytometry, BLI, Capture
100 μg
$500
Product Name
Size
MB-7976Cys
Conjugation Ready His Tag NovoBody™ Duo Binder
Twin-Strep-Tag-Cys*
None
Kit Features
ELISA, Flow Cytometry, BLI, Capture
100 μg
$500
Product Name
Size
MB-7982Bio
Biotin Labeled His Tag NovoBody™ Duo Binder
Twin-Strep-Tag
Biotin
Kit Features
ELISA, Flow Cytometry, BLI, Capture
100 μg
$550
Product Name
Size
MB-7982FITC
FITC Labeled His Tag NovoBody™ Duo Binder
Twin-Strep-Tag
FITC
Kit Features
ELISA, Flow Cytometry, BLI, Capture
100 μg
$550
*Contains a single free cysteine on the C-terminal region (distal from binding interface) available for custom chemical conjugation by the customer.
Anti-His NovoBody™ Duo Fc Fusion
Catalog Number
Product Name
Tag
Conjugation
Applications
Amount
Price
Product Name
Size
His Tag NovoBody™ Duo Fc Fusion
Human Fc
None
Kit Features
ELISA, BLI, Capture
100 μg
$500
Flow Cytometry Validation with MB-7974hFc
